Table 3.

Percent peptide depletion model based upon cysteine 1:10 (OECD, 2015).

Cysteine % depletion	Reactivity class	DPRA prediction
0% ≤ % depletion ≤ 13.89%	No/minimal reactivity	Negative
13.89% < mean % depletion ≤ 23.09%	Low reactivity	Positive
23.09% < mean % depletion ≤ 98.24%	Moderate reactivity
98.24% < mean % depletion ≤ 100%	High reactivity