Table 2.
Genotype data for selected single nucleotide polymorphisms upstream of CYP17A1. Genotypes were generated from a subset (n=232) of the hypertensive BRIGHT population. Major alleles are listed first and the given bases are from the forward strand sequence. The CYP17A1 location is relative to the first codon. HWE = Hardy Weinberg equilibrium.
SNP | ID | CYP17A1 Location | Chromosomal Location | Alleles | Minor Allele Frequency | HWE (p) | % Genotyped |
---|---|---|---|---|---|---|---|
rs743572 | 1 | −34 | 10:104597152 | A/G | 0.420 | 0.9276 | 96.9 |
rs2486758 | 2 | −362 | 10:104597480 | T/C | 0.183 | 0.9940 | 96.9 |
rs10883784 | 3 | −804 | 10:104597922 | C/T | 0.304 | 0.7485 | 100.0 |
rs10786713 | 4 | −1204 | 10:104598322 | A/G | 0.417 | 0.9121 | 99.6 |
rs10786714 | 5 | −1488 | 10:104598606 | G/C | 0.304 | 0.6991 | 99.6 |
rs138009835 | 6 | −1877 | 10:104598995 | G/A | 0.109 | 1.0000 | 100.0 |
rs2150927 | 7 | −2205 | 10:104599323 | G/A | 0.413 | 0.9276 | 99.1 |