Table 3.

Identified connections with significant group-wise differences. Significantly different connections are reported in terms of connectivity values and corrected P values. Connectivity values are reported as mean ± standard deviation (SD). Bold text shows identified connections with significant differences (corrected P < 0.001) between PD and SWEDD.

	Group-wise differences
	Connection	Number of fibers (mean ± SD)		Corrected P value
		PD	SWEDD
(a) Cortico-cortical connection	L_precentral-L_posteriorcingulate	4.6 ± 8.23	1.56 ± 2.89	0.028
	L_paracentral-L_superiorfrontal	1.18 ± 1.67	3.21 ± 6.29	0.039
	L_paracentral-L_posteriorcingulate	8.72 ± 8.32	3.48 ± 4.35	<0.001
	L_posteriorcingulate-L_superiorfrontal	11.7 ± 8.96	6.27 ± 6.23	0.003
	L_parsorbitalis-R_superiorfrontal	0.65 ± 3.33	2.18 ± 4.72	0.046
	R_paracentral-L_paracentral	0.65 ± 2.02	2.59 ± 4.5	0.014
	R_paracentral-R_posteriorcingulate	37.7 ± 23.47	17.8 ± 23.3	<0.001
	R_precentral-R_posteriorcingulate	13.1 ± 16.75	5.54 ± 14.3	0.034
	R_posteriorcingulate-R_superiorfrontal	43.67 ± 27.54	19.94 ± 21.7	<0.001
	R_posteriorcingulate-R_superiorparietal	10.45 ± 17.27	3.00 ±6.78	0.005
	R_rostralmiddlefrontal-R_inferiorparietal	1.42 ± 3.20	0.29 ± 1.17	0.045
(b) Cortico-subcortical connection	L_pallidum-L_frontalpole	0.77 ± 1.51	2.83 ± 6.40	0.045
	L_pallidum-L_postcentral	5.52 ± 9.17	16.08 ± 26.3	0.012
	L_putamen-L_precentral	14.5 ± 8.95	24.86 ± 24.48	0.013
	L_putamen-L_rostralmiddlefrontal	34.87 ± 30.86	21.83 ± 21.34	0.035
	L_caudate-L_rostralmiddlefrontal	37.5 ± 41.4	15.59 ± 24.66	0.027
	L_thalamusproper-L_rostralmiddlefrontal	7.27 ± 9.75	3.27 ± 5.02	0.007
	R_pallidum-R_superiorfrontal	1.50 ± 2.76	4.57 ± 7.97	0.022
(c) Subcortical connection	L_caudate-L_putamen	2.28 ± 3.34	5.59 ± 7.58	0.009
	R_putamen-R_pallidum	2.28 ± 2.33	4.51 ± 3.98	0.002
	Brainstem-L_putamen	3.80 ± 5.71	7.78 ± 10.96	0.046
	Brainstem-L_caudate	2.00 ± 4.29	4.51 ± 6.46	0.048
	Brainstem-R_thalamusproper	31.48 ± 18.72	42.08 ± 23.13	0.029