Figure 5.

Propranolol does not impair memory reconsolidation in the aquatic object recognition and object location tasks. Schematics of the behavioral protocols of the aquatic object recognition (A) and object location (B) tasks. Throughout training sessions, mice learned equally well to find the hidden platform and exhibited decreasing latencies (±SEM) over blocks of trials in the aquatic object recognition (C) and location (D) tasks. Performances during PT are expressed as the group mean (±SEM) preference index. The horizontal line represents equal exploration of the two objects. (E) For reactivation procedure of the aquatic version of the object recognition task, NaCl- but also propranolol-injected mice showed similar preference for the familiar object as compared to the new object (n = 11 per group). (F) For reactivation procedure of the aquatic version of the object location task, we obtained the same behavioral profile i.e., the two groups of mice spent significantly more time below the object that had remained in a familiar location than the object that had been introduced to a new location (n = 8 per group). ^###p < 0.001 index vs. chance level; 50%.