Figure 2. A CpG site in CLCN6 is indicative for survival in LBC1921 and LBC1936.

(A) A CpG site associated with the gene for the chloride transport protein 6 (CLCN6; cg05228408) was used to estimate age in the LBC1921 cohort. (B) Participants in the lowest and highest quartiles of Δ_age were subsequently analysed in Kaplan-Meier plots (K-M). Hazard ratio and cox-regression analysis of survival were subsequently tested with adjustment for chorological age and gender. (C, D) In analogy, the same analysis was performed for this CpG site using the LBC1936 cohort.