Table 4.
Trial | Registration No. | Treatment groups | Primary endpoint | Patients planned |
NEONAX | NCT02047513 | 2 cycles Gem + nab-paclitaxel neoadjuvant | DFS | 166 |
4 cycles Gem + nab-paclitaxel adjuvant | ||||
6 cycles Gem + nab-paclitaxel adjuvant | ||||
Perioperative mFOLFIRINOX | NCT02047474 | 3 cycles FOLFORINOX | DFS | 46 |
Neoadjuvant + adjuvant | ||||
NEOLAP | NCT02125136 | 2 cycles Gem + nab-paclitaxel | Conversion rate | 168 |
+ 2 × FOLFIRINOX | (including locally advanced PDAC) | |||
+ adjuvant 3 × Gem + nab-paclitaxel | ||||
4 cycles Gem + nab-paclitaxel | ||||
+ adjuvant 3 × Gem + nab-paclitaxel |
DFS: Disease-free survival; PDAC: Pancreatic ductal adenocarcinomas.