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. 2016 Mar 15;8(3):248–257. doi: 10.4251/wjgo.v8.i3.248

Table 4.

Ongoing neoadjuvant/borderline resectable trials

Trial Registration No. Treatment groups Primary endpoint Patients planned
NEONAX NCT02047513 2 cycles Gem + nab-paclitaxel neoadjuvant DFS 166
4 cycles Gem + nab-paclitaxel adjuvant
6 cycles Gem + nab-paclitaxel adjuvant
Perioperative mFOLFIRINOX NCT02047474 3 cycles FOLFORINOX DFS 46
Neoadjuvant + adjuvant
NEOLAP NCT02125136 2 cycles Gem + nab-paclitaxel Conversion rate 168
+ 2 × FOLFIRINOX (including locally advanced PDAC)
+ adjuvant 3 × Gem + nab-paclitaxel
4 cycles Gem + nab-paclitaxel
+ adjuvant 3 × Gem + nab-paclitaxel

DFS: Disease-free survival; PDAC: Pancreatic ductal adenocarcinomas.