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Efficacy of 21 as single agent and in combination with Cytotoxic in A549 non-small cell lung cancer (NSCLC) xenograft model. Oral in vivo efficacy profile of 21 on nude mice implanted with A549 NSCLC. N = 10 per group. Bars and arrows below the graph indicates treatment days of 21 (bar) and Paclitaxel (arrow).
