Table 1. Subtype Selectivity of Initial Lead Compounds.

	EC50 (nM)a
cmpd	hEP1	hEP2	hEP3	hEP4	hFP	hIP
5	N.T.b	5.6	3000	0.5	N.T.	N.T.
6	N.T.	8900	N.T.	4600	N.T.	47
7	1.4	7.9	0.8	33	32	11
8	160	3.9	260	1900	380	2500

^aAssay protocols are provided in the Supporting Information. EC₅₀ values represent the mean of two experiments.

^bN.T.: Not tested.