Effect of CypD inhibitor C-9 and
CsA on Aβ-induced decline of ATP levels. SK-N-SH cells were
treated with 5 μM oligomer Aβ plus: vehicle without inhibitor, C-9 at the indicated concentrations (10 and 20 μM),
CsA (1 μM), and Aβ alone (5 μM), respectively. After
48 h, ATP levels were determined in cell lysates. *P < 0.01: Aβ vs 10 μM C-9 + Aβ,
20 μM C-9 + Aβ, and CsA + Aβ, respectively.