Table 2. Lipinski Rule of Five Computational Studies for C-9 and Cyclosporin A.
| Lipinski properties | C-9 | cyclosporin A |
|---|---|---|
| mass (Daltons) | 470.574 | 1201 |
| hydrogen bond donor | 3 | 5 |
| hydrogen bond acceptors | 8 | 23 |
| LogP | 2.9 | 3.2 |
| molar refractivity | 122.88 | 328.44 |
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