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. 2016 Mar 14;6:23100. doi: 10.1038/srep23100

Figure 2. miR-499-5p inhibits cells proliferation and induces apoptosis in vitro and in vivo.

Figure 2

(A) Overexpression or inhibition of miR-499-5p significantly arrested or accelerated NSCLC cell proliferation. (B) Overexpression or inhibition of miR-499-5p induced or inhibited apoptosis in HOP62 or H522 cells. (C) Expression of Ki-67 was decreased or increased by overexpression or inhibition of miR-499-5p in xenograft tumor samples. (D) Caspase-3 was increased or decreased by overexpression or inhibition of miR-499-5p xenograft samples. Error bars represent the mean ± s.d. of three independent experiments. *p < 0.05; **p < 0.01; ***p < 0.001.