Table 2. Univariate and multivariate analyses for prognostic factors in patients with NSCLC.
Variables | Univariate | Multivariate | ||||
---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | |
Age, years (>65 vs ≤ 65) | 0.75 | 0.51–1.09 | 0.11 | — | — | — |
Gender (female vs male) | 1.18 | 0.83–1.69 | 0.34 | — | — | — |
Histology (squamous vs non-squamous) | 1.21 | 0.85–1.72 | 0.29 | — | — | — |
Pathological T (T3/4 vs T1/2) | 2.14 | 1.42–3.22 | <0.001 | 1.60 | 1.04–2.47 | 0.03 |
Lymph node metastasis (N1-3 vs N0) | 1.96 | 1.32–2.90 | 0.001 | 1.31 | 1.02–1.68 | 0.03 |
Distant Metastasis (M1 vs M0) | 5.06 | 2.33–11.00 | <0.001 | 3.72 | 2.19–6.34 | <0.001 |
miR-499-5p in tumor (high vs low) | 0.68 | 0.48–0.97 | 0.028 | 0.65 | 0.45–0.95 | 0.027 |
EGFR status (Mutation vs Wild type) | 0.96 | 0.68–1.37 | 0.83 | — | — | — |
HR, hazard ratio; CI, confidence interval; EGFR, epidermal growth factor receptor.