Skip to main content
. 2016 Mar 14;6:23035. doi: 10.1038/srep23035

Figure 3. The ER modulated gene set interaction network (ER-MGSIN) in breast cancer.

Figure 3

The MAGIC method can be also applied to identify modulated interactions among functions and pathways. (A) The ER-modulated functional gene set interaction network. The network was built by incorporating the 487 significant ER-modulated gene set interaction pairs composed of 604 individual gene sets. Each node and edge represent gene sets and ER-modulated interactions of pairs of gene sets, respectively. List and summary of ER-MRTPs are provided in Supplementary Table S4A,B. (B) Sub-network of oncogenic signature gene sets and their ER-modulated partners. (C) Sub-network of gene sets of TF targets and their ER-modulated partners.