Table 2.
miRNA verification results
miRNA | Average value X ± SD
|
P-value
|
||||
---|---|---|---|---|---|---|
Mucosa | Adenoma | Cancer | Mucosa/adenoma | Mucosa/cancer | Adenoma/cancer | |
Upregulated | ||||||
miR-135b-5p | 17.42±2.41 | 17.41±1.64 | 14.68±2.25 | 0.985 | 0.009 | 0.003 |
miR-183-5p | 21.23±3.69 | 27.36±2.35 | 21.48±2.72 | 0.001 | 0.85 | 0.001 |
miR-96-5p | 18.33±2.72 | 21.80±2.30 | 19.33±2.40 | 0.003 | 0.352 | 0.018 |
miR-18a-5p | 16.59±1.99 | 18.48±1.68 | 14.23±1.59 | 0.02 | 0.004 | 0.001 |
miR-21-3p | 24.99±2.52 | 17.03±3.96 | 16.90±5.40 | 0.001 | 0.001 | 0.949 |
miR-17-5p | 21.25±7.10 | 17.68±4.14 | 12.00±2.58 | 0.119 | 0.005 | 0.001 |
miR-182-5p | 23.51±3.91 | 25.12±3.16 | 19.04±2.74 | 0.28 | 0.004 | 0.001 |
miR-200a-5p | 22.20±6.26 | 22.90±3.54 | 13.86±3.40 | 0.74 | 0.001 | 0.001 |
miR-200c-3p | 23.90±4.74 | 21.42±3.83 | 13.63±3.63 | 0.172 | 0.001 | 0.001 |
Downregulated | ||||||
miR-204-5p | 12.60±5.15 | 16.73±3.75 | 16.35±4.94 | 0.035 | 0.083 | 0.833 |
miR-133a-3p | 9.16±3.74 | 14.93±2.26 | 15.21±3.11 | 0.001 | 0.001 | 0.802 |
miR-145-5p | 14.10±4.21 | 16.94±4.71 | 12.90±7.91 | 0.134 | 0.65 | 0.143 |
miR-145-3p | 11.55±4.00 | 14.78±4.74 | 15.26±7.46 | 0.085 | 0.143 | 0.851 |
miR-1 | 19.53±4.56 | 19.40±3.19 | 21.40±4.72 | 0.934 | 0.335 | 0.236 |
miR-125b-5p | 9.18±3.65 | 11.26±7.96 | 16.60±6.04 | 0.424 | 0.001 | 0.083 |
miR-139-5p | 13.50±3.69 | 17.30±6.79 | 21.42±3.64 | 0.102 | 0.001 | 0.078 |
miR-100-5p | 13.05±3.49 | 14.00±4.28 | 20.00±2.69 | 0.558 | 0.001 | 0.001 |
miR-30a-5p | 11.80±2.82 | 12.16±4.46 | 17.65±2.94 | 0.729 | 0.001 | 0.002 |
Abbreviation: miRNA, microRNA.