Table 1.
Tumor characteristics of microcalcification-associated, non-palpable breast cancer
| Coarse heterogeneous | Round/punctate | Amorphous | Fine pleomorphic | Fine linear or fine-linear branching | Total | |
|---|---|---|---|---|---|---|
| Pathology, n | 2 | 8 | 26 | 48 | 15 | 99 |
| DCIS, n (%) | 2 (100) | 4 (50.0) | 13 (50.0) | 30 (62.5) | 8 (53.3) | 57 (57.6) |
| Grade 1 | 0 (0) | 2 (50.0) | 4 (30.8)* | 9 (30.0) | 1 (12.5) | 16 (28.1) |
| Grade 2 | 1 (50.0) | 1 (25.0) | 9 (69.2)* | 10/30 (33.3) | 3 (37.5) | 24 (42.1) |
| Grade 3 | 1 (50.0) | 1 (25.0) | 0 (0)* | 11 (36.7) | 4 (50.0) | 17 (29.8) |
| IC, n, (%) | 0 (0) | 4 (50.0) | 13 (50.0) | 18 (37.5) | 7 (46.7) | 42 (42.4) |
| 0 (0) | 3 (75.0) | 10 (76.9) | 13 (72.2) | 5 (71.4) | 31 (73.8) | |
| T 2 | 0 (0) | 1 (25.0) | 3 (23.1) | 4 (22.2) | 2 (28.6) | 10 (23.8) |
| T 3 | 0 (0) | 0 (0) | 0 (0) | 1 (5.6) | 0 (0) | 1 (2.4) |
| Grade 1 | 0 (0) | 2 (50.0) | 2 (15.4) | 2 (11.1) | 1 (14.3) | 7 (16.7) |
| Grade 2 | 0 (0) | 2 (50.0) | 11 (84.6) | 14 (77.8) | 6 (85.7) | 33 (78.6) |
| Grade 3 | 0 (0) | 0 (0) | 0 (0) | 2 (11.1) | 0 (0) | 2 (4.8) |
| Nodal+ | 0 (0) | 0 (0) | 3 (23.1) | 7 (38.9) | 2 (28.6) | 12 (28.6) |
| IHC, n (%) | ||||||
| ER+ | 1 (50.0) | 6 (75.0) | 19 (73.1) | 35 (72.9) | 13 (86.7) | 74 (74.7) |
| PR+ | 0 (0) | 6 (75.0) | 21 (80.8)* | 25 (52.1)* | 11 (73.3) | 63 (63.6)* |
| HER2/neu+ | 1 (50.0) | 1 (12.5) | 5 (19.2) | 15 (31.3) | 7 (46.7) | 29 (29.3) |
| Triple− | 0 (0) | 1 (12.5) | 2 (7.7) | 3 (6.3) | 0 (0) | 6 (6.1) |
| Surgery, n (%) | ||||||
| BCT | 2 (100) | 6 (75.0) | 22 (84.6) | 31 (64.6)* | 12 (80.0) | 73 (73.7) |
| 1st SER | 1 (50.0) | 5 (62.5) | 20 (76.9) | 37 (77.1) | 13 (86.7) | 76 (76.8) |
| Final mastect. | 0 (0) | 2 (25.0) | 4 (15.4) | 17 (35.4)* | 3 (20.0) | 26 (26.3) |
| Outcome, n | 2 | 8 | 23 | 46 | 15 | 94 |
| RR, n (%) | 0 (0) | 2 (25.0) | 2 (8.7) | 3 (6.5) | 3 (20.0) | 10 (10.6) |
| MR, n (%) | 0 (0) | 0 (0) | 0 (0) | 3 (6.5) | 0 (0) | 3 (3.2) |
*
Considered significant p<0.05.
DCIS = ductal carcinoma in situ, IC = invasive carcinoma, IHC = immunohistochemisty, ER = estrogen receptor, PR = progesterone receptor, + = positive, − = negative, BCT = breast-conserving therapy, 1st SER = successful first excision rate, mastect. = mastectomy, RR = recurrence rate, MR = mortality rate.