Table 4.
Outcomes of CRS-1 according to the definition of AKI
| Period | All definitions | Studies/Patients | AKI | Studies/Patients | WRF | Studies/Patients | RRT | Studies/Patients | |
|---|---|---|---|---|---|---|---|---|---|
| Mortality | 28 days | 4.90 (3.68–6.52) | 33/56,860 | 5.14 (3.81–6.94) | 24/35,227 | 5.19 (2.78–9.70) | 12/51,805 | 9.16 (2.71–30.98) | 5/6,556 |
| 1 year | 2.08 (1.27–3.42) | 9/13,723 | |||||||
| ≥5 years | 1.90 (1.50–2.41) | 3/31,108 | |||||||
| LOSICU | 28 days | 1.46 (0.52–2.39) | 10/10,855 | 1.37 (0.41–2.33) | 9/10,758 | 3.00 (0.04–5.96) | 1/97 | 10.63 (3.51–17.74) | 3/5,799 |
| LOShosp | 28 days | 3.51 (1.78–5.24) | 13/8,733 | 3.94 (1.74–6.15) | 8/6,649 | 2.65 (0.75–4.54) | 5/2,084 | 20.20 (12.17–28.23) | 3/6,045 |
Data are presented as risk ratio (95% CI) for mortality and weighted mean difference (95% CI) for LOS. AKI = AKI defined by the RIFLE, AKIN or KDIGO classifications; WRF = AKI defined as worsening of renal function; RRT = AKI defined as the use of renal replacement therapy; CI = confidence interval.