Table 5.

Univariate and multivariate analyses for prognostic factors after diagnosis of brain metastases (BM)

	Univariate analysis		Multivariate analysis
Variable	HR (95% CI)	p value	HR (95% CI)	p value
Luminal HER2 vs. others	0.346 (0.165–0.724)	0.005	0.221 (0.103–0.474)	< 0.001
ECOG PS 0–1 vs. ≥ 2	0.506 (0.384–0.666)	< 0.001	0.386 (0.281–0.531)	< 0.001
Number of BM Single vs. multiple	0.693 (0.491–0.978)	0.036	0.601 (0.421–0.856)	0.005

HR = Hazard ratio; CI = confidence interval; ECOG = Eastern Cooperative Oncology Group; PS = performance status.