Table 4.

Relationship between brain structures and age-related change

Structures	Model 1		Model 2		Model 3
	β	p	β	p	β	p
Total grey matter/ICV	0.139	0.055	0.195	0.024	0.249	0.137
Ventricles/ICV	−0.366	<0.001	−0.164	0.082	−0.384	0.004
Left MTLa	0.287	<0.001	0.277	0.005	0.376	0.013
Right MTLa	0.219	0.005	0.112	0.335	0.228	0.145

Rows represent separate models. ICV = Intracranial volume. Model 1–adjusted for age, adult ability, % saturated fat, LEP, physical activity and systolic blood pressure. Model 2–adjusted for age alone. Model 3–no adjustment.

^aRegional grey matter measures are adjusted for intracranial volume and brain folding during processing.