Table 4.
Hepatitis delta virus serological profiles of patients
|
HDV markers |
HCV markers | ||||||
|
Serum HDV-RNA |
Serum HCV-RNA |
||||||
| Genotype | Anti-HD IgM | Status1 | Log10 (copies/mL) (range) | VC | Anti-HCV | HCV-RNA | |
| Pat #1 | Und | Negative | Positive | 5.90 ± 0.31 (5.53-6.11) | 0.05 | Negative | NA |
| Pat #2 | A | Negative | Positive | 5.69 ± 0.05 (5.64-5.72) | 0.01 | Negative | NA |
| Pat #3 | E | Negative | Positive | 5.11 ± 0.12 (5.02-5.20) | 0.02 | Negative | NA |
| Pat #4 | A | Negative | Positive | 4.38 ± 1.64 (2.60-5.84) | 0.37 | Negative | NA |
| Pat #5 | A | Negative | Positive | 6.47 ± 0.64 (5.70-7.18) | 0.10 | Negative | NA |
| Pat #6 | D | Positive | Positive | 4.55 ± 2.26 (1.08-5.75) | 0.50 | Negative | NA |
| Pat #7 | E | Positive | Positive | 4.01 ± 0.31 (3.57-4.43) | 0.08 | Negative | NA |
| Pat #8 | D | Positive | Positive | 4.13 ± 0.35 (3.89-4.38) | 0.08 | Negative | NA |
| Pat #9 | A | Positive | Fluctuating | 2.14 ± 0.99 (1.00-3.31) | 0.46 | Negative | NA |
| Pat #10 | D | Positive | Fluctuating | 4.07 ± 1.72 (1.00-5.07) | 0.42 | Negative | NA |
| Pat #11 | A | Negative | Positive | 5.47 ± 1.33 (4.53-5.47) | 0.24 | Negative | NA |
| Pat #12 | D | Positive | Positive | 4.76 ± 1.46 (1.70-6.22) | 0.31 | Negative | NA |
| Pat #13 | A | Positive | Positive | 4.53 ± 0.16 (4.41-4.64) | 0.04 | Negative | NA |
| Pat #14 | D | Negative | Fluctuating | 3.08 ± 2.95 (1.00-5.17) | 0.96 | Positive | Negative |
| Pat #15 | D | Negative | Negative | NA | NA | Positive | Negative |
| Pat #16 | E | Positive | Positive | 6.26 ± 0.74 (5.74-6.78) | 0.12 | Negative | NA |
Evolution of HDV-RNA during follow-up. Fluctuating is defined as a patient with alternating positive and negative samples. HDV genotype was I in the 16 samples analyzed. The number of patients with HCV infection was too low to perform statistical analysis. Und: undetermined genotype due to HBV-DNA negativity. VC: Variation coefficient; NA: Not applicable; HBV: Hepatitis B virus; HCV: Hepatitis C virus; HDV: Hepatitis delta virus.