Fig. 5.

The product of inductions from the C-terminal and core domains potentially reveals WT saturation. a Scatterplot where the horizontal coordinate equals induction by WT AvrPto relative to the CTD⁻/CD⁻ and includes all genes strongly up- or down-regulated by AvrPto. The product of the gene inductions by the CD and CTD was calculated by multiplying the inductions relative to the CTD⁻/CD⁻. Each gene is plotted 2 times with the same X coordinate and a variable Y coordinate based on identity, indicated by color. b Histograms of residual values of WT compared to the CD⁻/CTD⁻ compared to the model combining the effects of both domains (gray). Histograms are binned according to value in 2^(1/16) sized bins. A simulated random lognormal distribution is shown in red, and contains the same number of data points as the set plotted from the transcriptome. The sets plotted are either those in Fig. 5a down-regulated (upper) or up-regulated (lower) by AvrPto. The sum of bin heights has been set equal to 1. Probability plots are included in Additional file 7: Figure S3 for both normal and log-normal distributions