Table 3.
Toxicity profile for all 110 patients
| Toxicity | Grade 2 N |
Grade 3 N |
Grade 4* N |
Hospitalizations for grade 3/4 N (%) |
|---|---|---|---|---|
| Gastrointestinal | ||||
| Nausea | 1 | 2 | 2/2 (100%) | |
| Mucositis | 2 | 1 | 1/3 (33%) | |
| Infection | ||||
| Neutropenic infection | 3 | 21 | 4 | 26/28 (93%) |
| Non-neutropenic infection | 2 | 1 | 1/3 (33%) | |
| Febrile neutropenia | 50 | 50/50 (100%) | ||
| Hemorrhage | ||||
| Gastrointestinal hemorrhage | 7 | 7/7 (100%) | ||
| Other Mucosal (Oral) | 1 | 1/1 (100%) | ||
| Cardiac | ||||
| Hypotension | 1 | 1 | 1/2 (50%) | |
| Atrial fibrillation | 1 | 1/1 (100%) | ||
| Metabolic | ||||
| Elevated alkaline phosphate | 1 | 0/1 |