Table 2.
Distribution of MIF-173 polymorphism genotypes and allele frequencies in patients and controls.
| MIF-173 | Control (N = 202) |
Patients (N = 124) |
χ2 | df | p-value | OR (95% CI) | ||
|---|---|---|---|---|---|---|---|---|
| Count | Frequency | Count | Frequency | |||||
| Genotype | ||||||||
| GG | 122 | 0.60 | 95 | 0.77 | 10.2 | 2 | 0.006 | |
| GC | 64 | 0.32 | 26 | 0.21 | ||||
| CC | 16 | 0.08 | 3 | 0.02 | ||||
| Allele frequency | ||||||||
| G | 308 | 0.76 | 216 | 0.87 | Ref. | |||
| C | 96 | 0.24 | 32 | 0.13 | 11.5 | 1 | 0.0007 | 0.48 (0.31–0.74) |
| Allele carriage | ||||||||
| (GG + GC) vs. CC | 186 | 0.92 | 121 | 0.98 | 4.2 | 1 | 0.04 | 3.5 (0.99–12.2) |
| (CC + GC) vs. GG | 80 | 0.4 | 29 | 0.23 | 9.1 | 1 | 0.003 | 0.47 (0.28–0.77) |
Significant findings are shown in bold; N, number.