Table 3.
Distribution of MIF-794 repeat genotypes and allele frequencies in patients and controls.
| MIF-794[CATT] | Control (N = 202) |
Patients (N = 124) |
χ2 | p-value | OR (95% CIs) | |||
|---|---|---|---|---|---|---|---|---|
| Count | Frequency | Count | Frequency | |||||
| Genotype | ||||||||
| 5/5 | 19 | 0.09 | 3 | 0.02 | 5.96 | 0.02 | 0.24 (0.07–0.82) | |
| 5/6 | 64 | 0.32 | 35 | 0.28 | 0.4 | 0.5 | 0.9 (0.5–1.4) | |
| 5/7 | 7 | 0.03 | 3 | 0.02 | 0.3 | 0.6 | 0.7 (0.18–2.7) | |
| 5/8 | 4 | 0.02 | 0 | 0.00 | 2.5 | 0.1 | 0.98 (0.96–1) | |
| 6/6 | 82 | 0.41 | 69 | 0.56 | 7.0 | 0.008 | 1.8 (1.17–2.9) | |
| 6/7 | 18 | 0.09 | 10 | 0.08 | 0.07 | 0.8 | 0.9 (0.4–2) | |
| 6/8 | 6 | 0.03 | 1 | 0.01 | – | 0.3 | – | |
| 7/7 | 2 | 0.01 | 2 | 0.02 | – | 0.6 | – | |
| 7/8 | 0 | 0.00 | 0 | 0.00 | – | – | – | |
| 8/8 | 0 | 0.00 | 1 | 0.01 | – | – | – | |
| X allele carriage | ||||||||
| (5/5 + 5/X) vs. X/X | 94 | 0.47 | 41 | 0.33 | 5.7 | 0.02 | 0.57 (0.36–0.9) | |
| (X/X + 5/X) vs. 5/5 | 183 | 0.91 | 121 | 0.98 | 6.0 | 0.01 | 4.2 (1.2–14.5) | |
| Allele freq. | ||||||||
| 5 | 113 | 0.28 | 44 | 0.18 | 8.8 | 0.003 | 0.56 (0.38–0.82) | |
| 6 | 252 | 0.62 | 184 | 0.74 | 9.7 | 0.002 | 1.7 (1.2–2.5) | |
| 7 | 29 | 0.07 | 17 | 0.07 | 0.03 | 0.9 | 1 (0.51–1.8) | |
| 8 | 10 | 0.02 | 3 | 0.01 | – | 0.4 | – | |
| X allele freq. | 291 | 0.82 | 204 | 0.72 | 8.8 | 0.003 | 1.8 (1.22–2.66) | |
Significant findings are shown in bold; N, number; X refers to 794 CATT alleles 6–8.