Table 2. Treatments and Outcomes in Reported Cases of Autoimmune Stiff Person Syndrome and Its Variants.

				Treament													Outcome
Reference	Reported Diagnoses at Presentation	Age and Sex At Presentation	Number of Symptomatic Months Before Presentation	Antibiotics	Antiepileptics	Antipsychotics	Baclofen	Benzodiazepines	Botulinum Toxin Injections	Intravenous Immune Globulin	Other Agents Or Interventions	Plasmapheresis	Rituximab	Steroids	Steroid–Sparing Immunosuppression	Surgery: Spinal Cord Stimulator	Improvement or Resolution	Stabilization Without Improvement	One or More Relapses Mentioned	Worsening and/or Death
Lobo et al.44	SP	41F	84					+	+				+				+
Scavone et al.24	SP	66M								+							+
Awad et al.23	A	48F								+			+	+				+
Castelnovo et al.45	SL	63F	36					+		+							+
Cuturic et al.46	SP, ED	35F	24				+	+		+	+						+
Ehler et al. 6	SP	61M	<1				+	+				+		+	+		+		+
Gnanapavan et al.47	SP	45M	60				+	+		+	+		+		+		+		+
Goldkamp et al.48	SP	27F					+	+		+	+			+			+
Mas et al.37	E, PERM	60M	<1															+
	PERM	48M	2					+		+	+			+			+
	SL, SP	33F	3				+	+		+				+			+		+
Piotrowicz et al.49	PERM	58M	>1					+				+		+	+		+		+
Turner et al.27	PERM	28M	1		+															+
Witherick et al.28	SP	69M								+	+				+		+		+	+
Anagnostou et al.50	SL	40F	108					+	+								+
Amyradakis et al.51	SP	F	<1					+			+						+		+
Fekete and Jankovic52	SP	12M	84		+		+	+		+	+		+				+
Fernandes et al.53	SP	50F	48				+	+		+							+
	A, E	52F	<1		+			+		+				+	+
Iizuka et al.25	PERM	61F	1.5					+		+				+	+		+		+
Lorenzoni et al.33	SL	10F						+		+							+
	SP	40M					+	+		+							+
	SP	42M					+	+		+							+
Najjar, at al.22	S	19F				+				+		+		+			+		+
Peeters et al.36	PERM	37F	1				+	+				+		+			+		+
Qureshi et al.54	SP	56M	72		+			+		+	+	+	+	+			+
Tsai et al.55	66M	SP	4				+	+		+				+	+		+		+
Baroncini et al.26	A, LE	44F	36		+					+		+	+	+			+
Clardy et al.14	SP	8F	<12				+	+		+		+			+		+
	SP	26M	168				+	+						+				+
	SP	51F	552				+	+		+					+			+
	SP	49M	528															+
	SL	14F	156					+		+							+
	ST	17M	36				+	+	+		+	+					+
	PERM	13F	<12					+		+		+	+					+
De la Casa-Fages et al.56	SP	59F	10		+		+	+	+	+		+		+	+		+
	SP	48M	240					+		+		+		+	+		+
Damasio et al.57	PERM	1F	<1	+	+			+		+				+			+		+
Marinovic et al.58	SP	51F						+			+							+
Nakane et al.59	SP							+		+					+		+		+
	SP							+				+		+	+		+		+
O’Toole et al.60	SP	72F	12
Sidransky et al.61	SP	34	6				+	+		+	+						+
Sengupta et al.62	A, SP	F											+		+		+		+
Vetrugno et al.63	OT, SP	77F	1					+		+							+		+
	OT, SP	55F	12					+		+							+
Bordelon et al.64	SP	60F	108				+	+		+	+			+			+
Enuh et al.65	SP	20F	12				+	+		+	+						+
Fourlanos et al.66	SP	78F	300							+		+					+
	SP	72F	6				+			+						+	+
Georgieva et al.67	A, E	45M								+		+			+		+		+
Ho et al.68	SP	43F					+	+						+			+
Jung et al.69	SP	55F	12					+									+
	SP	58F	15				+	+									+
	E, SP	49F	10				+	+						+			+
Pagano et al.30	SP	45M										+					+
	A, SP	65F								+		+						+
	SP	48F								+		+					+
	SP	61F								+		+					+
	SP	34F								+		+					+
	A, SP	50F										+					+
Rana et al.70	SP	50F	30
Sanders et al. 71	SP	48F			+		+	+		+	+	+			+		+
	SP	30F	24				+	+		+	+	+					+
Stern et al.72	PERM	40M	<1				+	+		+		+		+			+		+
Wuerfel et al.73	B, E	2M	12		+									+			+
Bowen et al.29	C, SP	49F	24
	C, SP	68F	84							+										+
Farooqi et al.74	E	23F	48		+					+		+		+	+			+	+

Abbreviations: A, Ataxia; B, Behavioral Changes; C, Corticobasal Syndrome; E, Epilepsy; ED, Eating Disorder; F, Female; LE, Limbic Encephalitis; M, Male; OT, Orthostatic Tremor; PERM, Progressive Encephalomyelitis with Rigidity and Myoclonus; S, Schizophrenia; SL, Stiff Limb Syndrome; SP, Stiff Person Syndrome; ST, Stiff Trunk Syndrome.