Table 4. Reported Cases of Cryptogenic Stiff Person Syndrome and Its Variants.

				Symptoms									History or Examination Findings											Testing								Treatment						Outcome
Reference	Reported Diagnosis	Age And Sex at Presentation	Number Of Symptomatic Months Before Presentation	Bulbar Dysfunction	Genitourinary Dysfunction	Difficulty Moving Limb	Falls	Gait Difficulties (Including Ataxia)	Pain	Axial Stiffness Or Hyperlordosis	Autonomic Instability (Besides Genitourinary Dysfunction)	Concomitant Autoimmunity	Cramps/Spasms	Encephalopathy Or Psychiatric/Behavioral Changes	Hyperekplexia	Hyperreflexia	Limb Posturing/Dystonia	Limb Stiffness/Rigidity	Myoclonus	Seizures	Weakness	Documentation Of Autoantibody Testing	Serum Anti–Gad Or Anti–Glyr Antibodies	CSF Oligoclonal Bands	Electroencephalographic Abnormalities	Electromyography Findings Consistent With SP	MRI Brain Abnormalities (Incidental Findings Excluded)	Antiepileptics	Baclofen	Benzodiazepines	Botulinum Toxin Injections	Intravenous Immune Globulin	Other agents or interventions	Plasmapheresis	Steroids	Steroid–sparing immunosuppression	Surgical intervention	Improvement or resolution	1 or more relapses	Stabilization without improvement
Ughratdar et al.32	SL, SP	44M	168						+				+		+		+					+	–			+			+	+			+				+	+
Hegyi.40	SP	24F	9			+		+	+	–			+	+			+	+			+	–								+			+					+
Iwata et al.34	SL	29M	24					+	+				+		+	+	+	+				+	–	+	–	+	–			+			+					+
Prasad89	SP	51M	6				+		+		–		+	+	+					+	+	–			–		–		+	+			+							+
Sanefuji et al.90	SP	7F	<1					+	+				+	+	+	–			–			+	–		–	+	+		+	+		+	+		+			+
Schreiber et al.41	SP	75F	36				+	+	+	+			+	–	+	+		+				+	–			–	–		+	+			+					+
Lorenzoni et al.33	SP	43M						+	+	+		T, V	+		+	+		+				+	–			+			+	+								+
Clardy et al.14	SP	13M	2							+		–	+			–						+	–										+	+	+			+
Newton et al.42	SP	48M		+				+	+	+			+			–		+				+	–						+	+	+							+
Vicente–Valor et al.43	SP	40M	72			+		+	+	+	+		+		+	+		+				+	–			+		+	+	+		+	+		+	+		+
Sharma et al. 91	SP	65M	6					+	+	+			+	+		–		+				+	–			+			+	+					+			+
Pakeerappa et al.92	SP	48M	17							+			+					+				+	–						+	+	+		+					+
Ueno et al.35	PERM	48F	<1		+		+	+	+	+	+		+	+		+		+	+			+	–	–		+	+	+		+		+	+		+	+		+	+