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Piperine analogs that decrease MIC of ciprofloxacin in MDR S. aureus strain over-producing NorA (1199B); (a) structure of piperine; (b) the general structure of the tested compounds; (c) the most active compounds 13, 16 and 20; (d) Abilities of compounds 13, 16, 20 to increase efficacy of ciprofloxacin [33].
