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Phenylpiperidine selective serotonin reuptake inhibitor (PSSRI)-based EPIs of S. aureus. (a) Paroxetine; (b) general structures (A and B) of the investigated piperidine derivatives; (c) the most promising EPIs found within the assays (15, 16, 23, 24) and their EPIs potency, expressed as IC50 values for inhibition of NorA (SA-K2361) or MepA (SA-K2886) in comparison to those of paroxetine [35,37].
