. 2013 Feb 18;2(1):58–72. doi: 10.3390/antibiotics2010058

Table 1.

Antibacterial activity of synthetic phenothiazines by in vitro screening.

Phenothiazine	MIC µg/mL		Bacteriostatic/ Bactericidal
Phenothiazine	Gram +ve	Gram –ve	Bacteriostatic/ Bactericidal
CPZ	10–50	25–100	Bacteriostatic for Gm −ve, Bactericidal for Gm +ve
Pr	10–50	10–100	Bacteriostatic
Pz	50–200	100–200	Bacteriostatic
Pc	25–100	50–400	Bacteriostatic
Md	10–100	25–200	Bactericidal
Fz	10–100	10–100	Bactericidal
Tm	10–100	10–100	Bactericidal
Tf	10–100	25–200	Bactericidal
Tp	2–50	2–100	Bactericidal
Tz	32–64	100–800	Bacteriostatic for Gm –ve, Bactericidal for Gm +ve
Tz	50–800	100–800	Bacteriostatic for Gm –ve, Bactericidal for Gm +ve
Fp	5–50	10–100	Bacteriostatic

Please note: The bactericidal effect can be reached with multiple of the MICs. CPZ, chlorpromazine; Pr, promazine; Pz, promethazine; Pc, prochlorperazine; Md, methdilazine; Fz, fluphenazine; Tm, trimeprazine; Tf, trifluoperazine; Tp, triflupromazine; Tz, thioridazine; Fp, flupenthixol.