Table 2.
Guideline Compliance and Order Set Utilization.
| Historical Group n = 165 |
Intervention Group n = 146 |
p Value | Intervention Group With Use of Order Set n = 45 | Intervention Group Without Use of Order Set n = 101 | p Value | |
|---|---|---|---|---|---|---|
| Order set utilization | 2 (1.2) | 45 (30.8) | <0.001 | NA | NA | NA |
| Treatment compliant with guideline | 115 (69.7) | 104 (71.2) | 0.605 | 36 (80.0) | 68 (67.3) | 0.165 |
| Reasons for Non-Compliance | ||||||
| Given metronidazole for severe infection | 10/50 (20.0) | 20/45 * (44.4) | 0.015 | 4/9 (44.4) | 16/36 * (44.4) | 1.000 |
| Given vancomycin for mild/moderate infection | 12/50 (24.0) | 5/45 (11.1) | 0.116 | 1/9 (11.1) | 4/36 (11.1) | 1.000 |
| Combination therapy given but not needed | 6/50 (12.0) | 7/45 (15.6) | 0.767 | 3/9 (33.3) | 4/36 (11.1) | 0.131 |
| Patient required combination therapy but did not receive | 17/50 (34.0) | 4/45 (8.9) | 0.006 | 0/9 (0.0) | 4/36 (11.1) | 0.569 |
| Vancomycin taper indicated but not given | 2/50 (4.0) | 4/45 (8.9) | 0.418 | 1/9 (11.1) | 3/36 (8.3) | 1.000 |
| Other ** | 3/50 (6.0) | 5/45 (11.1) | 0.470 | 0/9 (0.0) | 5/36 (13.9) | 0.566 |
All data presented as number (%); * Some patients had multiple reasons for noncompliance with guideline; ** Other reasons included incorrect dosing or route of antibiotics, allergy to preferred agent, drug interaction with preferred agent, previously treated with alternative agent.