Table 2.
The MIC distribution of each antimicrobial agent against 26 clinically isolated N. gonorrhoeae strains in the patients with GU for whom it was possible to judge microbiological outcomes. Eradication means no N. gonorrhoeae detected by culture after treatment with AZM ER. Failure means N. gonorrhoeae detected by culture after treatment with AZM ER.
Antimicrobial agents | Outcome | MICs | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
≦0.001 | 0.002 | 0.004 | 0.008 | 0.015 | 0.03 | 0.06 | 0.12 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | 32 | 64 | ||
PCG | Eradication | - | - | - | - | 2 | - | 1 | 5 | 5 | 4 | 4 | 2 | - | - | - | - | - |
Failure | 1 | 1 | 1 | |||||||||||||||
CTRX | Eradication | 1 | 3 | 2 | 3 | 4 | 2 | 6 | 2 | - | - | - | - | - | - | - | - | - |
Failure | 1 | 1 | 1 | |||||||||||||||
CDZM | Eradication | - | 1 | 2 | 4 | - | 3 | 7 | 5 | 1 | - | - | - | - | - | - | - | - |
Failure | 1 | 2 | ||||||||||||||||
CFIX | Eradication | - | 1 | 1 | 3 | 2 | - | 3 | 8 | 3 | 2 | - | - | - | - | - | - | - |
Failure | 1 | 1 | 1 | |||||||||||||||
SPCM | Eradication | - | - | - | - | - | - | - | - | - | - | - | - | - | 3 | 14 | 6 | - |
Failure | 1 | 2 | ||||||||||||||||
AZM | Eradication | - | - | - | - | - | - | 4 | 3 | 3 | 6 | 6 | 1 | - | - | - | - | - |
Failure | 1 | 1 | 1 | |||||||||||||||
CPFX | Eradication | - | - | 1 | 2 | 2 | - | - | - | - | - | - | 1 | - | 4 | 4 | 8 | 1 |
Failure | 3 | |||||||||||||||||
LVFX | Eradication | - | - | 1 | 2 | 2 | - | - | - | - | - | 1 | 1 | 4 | 8 | 4 | - | - |
Failure | 3 |