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. Author manuscript; available in PMC: 2016 Mar 14.
Published in final edited form as: Biol Blood Marrow Transplant. 2015 Jan 22;21(5):866–872. doi: 10.1016/j.bbmt.2015.01.017

Table 1. Patient- and Transplantation-Characteristics.

Variable Total Study Group
Year of Transplant 1995-1999 16 (13%)
2000-2006 40 (32%)
2007-2013 68 (55%)
Age of Patients < 50 41 (33%)
50-60 47 (38%)
>60 36 (29%)
Median (range) (IQR) 55 (18-72), (47-62)
Patient Gender Male 83 (67%)
KPS <90 25 (21%)
90/100 97 (80%)
Recipient CMV Serostatus Negative 57 (46%)
Positive 67 (54%)
Donor Type RD/URD Match 67 (54%)
RD/URD MM 8 (7%)
UCB 5+6/6 24 (19%)
UCB 4/6 25 (20%)
Conditioning MAC 47 (38%)
RIC: w/ ATG 52 (42%)
RIC: w/o ATG 25 (20%)
GvHD Prophylaxis CSA/MMF 75 (61%)
CSA containing 31 (25%)
Other 18 (15%)
Diagnosis MDS-NOS 24 (19%)
MDS - RA 5 (4%)
MDS - RAEB-1 34 (27%)
MDS - RAEB-2 30 (24%)
MDS - RARS 4 (3%)
MDS - RCMD 21 (17%)
RCMD - RS 6 (5%)
Months from Diagnosis to Transplant: Median (range), (IQR) 6 (1-371), (4-13)
Therapy-related MDS No 94 (77%)
Yes 28 (23%)
Blast at alloHCT <=2% 74 (60%)
>2-<5% 33 (27%)
5-10% 17 (14%)

Abbreviations: AlloHCT, allogeneic hematopoietic cell transplantation; CMV, cytomegalovirus; CSA, cyclosporine; GVHD, graft-versus-host disease; IPSS, International Prognostic Scoring System; R-IPSS, International Prognostic Scoring System-revised; KPS, Karnofsky performance status; MAC, myeloablative conditioning; MDS, myelodysplastic syndrome; MDS-U, MDS- unclassifiable; MRD, matched related donor; MMRD, mismatched related donor; MTX, methotrexate; RIC, reduced intensity conditioning; MMF, mycophenolate mofetil; MDS, myelodysplastic syndrome; NOS, not otherwise specified; RA, refractory anemia; RAEB, refractory anemia with excess blasts; RARS, refractory anemia with ringed sideroblasts; RD, related donor; RCMD, refractory cytopenias with multilineage dysplasia; RCMD/RS, RCMD with ringed sideroblasts; UCB, umbilical cord blood; URD, unrelated donor; WHO, World Health Organization