Table 2. Cytogenetic risk scores by various systems at diagnosis and alloHCT.
| Scoring System | Cytogenetics Risk Score | At Diagnosis | At AlloHCT | Change in cytogenetic score between Diagnosis and AlloHCT | |
|---|---|---|---|---|---|
| IPSS | Good | 35 (29%) | 44 (37%) | Improved | 17 (15%) |
| Intermediate | 28 (23%) | 26 (22%) | No change | 91 (78%) | |
| Poor | 58 (48%) | 50 (42%) | Progression | 9 (8%) | |
|
| |||||
| R-IPSS | Very good | 2 (2%) | 1 (1%) | Improved | 16 (14%) |
| Good | 34 (28%) | 44 (37%) | No change | 91 (78%) | |
| Intermediate | 24 (20%) | 24 (20%) | Progression | 10 (9%) | |
| Poor | 32 (26%) | 25 (21%) | |||
| Very poor | 29 (24%) | 25 (21%) | |||
|
| |||||
| TSCS | Favorable | 63 (52%) | 71 (59%) | Improved | 13 (11%) |
| Adverse | 59 (48%) | 49 (41%) | No change | 102 (86%) | |
| Progression | 3 (3%) | ||||
|
| |||||
| MK | No | 83 (70%) | 90 (75%) | Improved | 9 (8%) |
| Yes | 36 (30%) | 30 (25%) | No change | 104 (90%) | |
| Progression | 3 (3%) | ||||
Abbreviations: AlloHCT, allogeneic hematopoietic cell transplantation; IPSS, International Prognostic Scoring System; R-IPSS, International Prognostic Scoring System-revised; MK, monosomal karyotype; TSCG transplant-specific cytogenetic grouping.