Skip to main content
. Author manuscript; available in PMC: 2016 Mar 14.
Published in final edited form as: J Med Chem. 2015 Dec 10;58(24):9562–9577. doi: 10.1021/acs.jmedchem.5b01110

Figure 3. Primary sequence alignment of human CCK1R and CCK2R.

Figure 3

Shown is an alignment of the sequences of the human CCK1R and CCK2R, identifying predicted transmembrane (TM) segments (underlined), as well as the residues believed to line the intramembranous pocket that are distinct in these two receptors. These residues were exchanged in the chimeric constructs utilized for this project.