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. 2004 Jul 20;2(9):e275. doi: 10.1371/journal.pbio.0020275

Figure 2. APOBEC3G Has Been Under Positive Selection for at Least 33 Million Years.

Figure 2

The ω values and actual numbers of non-synonymous and synonymous changes (R:S, included in parentheses) in APOBEC3G are indicated on the accepted primate phylogeny (Purvis 1995) that includes five hominids, five OWMs, and two NWMs. OWMs diverged from hominids about 23 million years ago, whereas NWMs diverged around 33 million years ago (Nei and Glazko 2002). ω values were calculated using the PAML package of programs using the free-ratio model that allows ω to vary along each branch. In some instances, zero synonymous substitutions lead to an apparent ω of infinity. HIV/SIV-infected species are indicated by asterisks.

DOI:10.1371/journal.pbio.0020275.g002