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. Author manuscript; available in PMC: 2016 Mar 14.
Published in final edited form as: Informatics (MDPI). 2014 May 30;1(1):72–99. doi: 10.3390/informatics1010072

Table 2.

Clinical Tracer Imaging Modality Sample Size Sensitivity Specificity Positive and negative predictive values Evaluated and Recommended for Endocarditis
18F-FDG PET/CT 72 39% 93% 64%
82%		 ×
99mTc-HMPAO-WBC SPECT/CT 51 90% 100% 100%
94%		 ✓
99mTc-anti-NCA-95 Scintigraphy SPECT 72 79% 82% × ✓
111In-DPTA-anti-Fibrin mAb Scintigraphy 86 97% 72% × N/A
99m-Tc-DTPA-anti-Fibrin mAb Scintigraphy 94 84.2% 97.6% × N/A
Pre-clinical Probe: Host based Imaging Modality Pre-clinical Probe: Pathogen based Imaging Modality Pre-clinical Probe: Antibiotic based Imaging Modality
99mTc-Stannous Pyrophosphate Scintigraphy Bis-dipicolylamine-Zinc(II)-Carbocyanine Optical Vancomycin-800CW Optical
99mTc-Annexin V Scintigraphy AF680-ProThrombin FMT/CT 3H-Spiramycin Auto-radiography
111In-Platelets Scintigraphy 64Cu-DPTA-ProThrombin PET/CT
Gd-DPTA-anti-Fibrin monoclonal antibody MRI 64Cu-DOTA-anti-pilin monoclonal antibody PET/CT