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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Am J Transplant. 2015 May 27;15(12):3215–3223. doi: 10.1111/ajt.13356

Table 2.

Changes in Characteristics of Deceased Donors Labeled IRD Under Old and New Guidelines

Old Guidelines New Guidelines Interaction p-
value**
Donor Characteristic Non-IRD
N=2998
IRD
N=424
Non-IRD
N=2804
IRD
N=680
RR (95% CI)
Overall (%) 87.7 12.3 80.5 19.5
Male (%) 58.9 64.4 59.1 66.9 1.07 (0.85-1.36) 0.6
Age (%)
<18 months 2.1 3.1 2.0 1.0 0.44 (0.18-1.04) 0.06
18 mnths-18 yrs 8.7 4.3 8.7 3.7 0.96 (0.53-1.74) 0.9
18-40 yrs 32.1 61.1 31.0 60.3 Reference
41-50 yrs 20.6 16.3 20.2 18.2 1.18 (0.87-1.61) 0.3
51-60 yrs 22.2 10.9 23.4 13.4 1.24 (0.86-1.79) 0.2
>60 yrs 14.2 4.5 14.9 3.4 0.81 (0.44-1.49) 0.5
Race (%)
White 64.4 72.6 66.0 67.4 Reference
African American 18.0 13.4 16.5 18.1 1.52 (1.11-2.10) 0.01
Hispanic 14.0 12.7 13.6 12.1 1.08 (0.76-1.52) 0.7
Other 3.6 1.2 3.9 2.5 2.13 (0.81-5.65) 0.2
BMI (mean) 27.7 26.7 28.0 26.7 0.99 (0.98-1.01) 0.7
ECD (%) 26.2 9.2 26.4 11.6 1.34 (0.91-1.97) 0.1
Serum Creatinine
(mean)
1.5 1.5 1.4 2.0 1.11 (1.05-1.17) <0.001
Cause of Death (%)
Anoxia 28.9 45.5 30.5 47.9 Reference
CBV/Stroke 37.5 21.0 37.5 19.1 0.99 (0.73-1.34) 0.9
Head Trauma 30.7 31.6 28.9 30.6 1.06 (0.82-1.36) 0.6
CNS Tumor/Other 2.8 1.9 3.1 2.4 1.20 (0.53-2.72) 0.7
**

P-value for Interaction between characteristic and era (old guidelines, February 1-July 1 2013 new guidelines, February 1-July 1 2014

RR = Relative Risk

IRD = Increased Risk for Disease Transmission