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. Author manuscript; available in PMC: 2016 Mar 14.
Published in final edited form as: Life Sci. 2014 Dec 11;122:1–7. doi: 10.1016/j.lfs.2014.12.001

Figure 2. Anti-TLR4 treatment decreases NFκB p65 phosphorylation and attenuates noradrenaline-induced constriction in mesenteric resistance arteries from SHR.

Figure 2

Cumulative concentration-response curves to noradrenaline in the presence of vehicle or pyrrolidine (NFκB inhibitor), in mesenteric resistance arteries from (A) Wistar and (B) SHR treated with IgG or anti-TLR4. (C) Protein expression of phosphorylated and total NFκB p65 in mesenteric resistance arteries from Wistar and SHR treated with IgG or anti-TLR4. Each curve point represents the mean ± SEM of maximal response to each concentration of noradrenaline. Bar graphs show the relative expression of proteins (mean ± SEM) after normalization to β-actin. On the top are representative Western blotting images of protein expression. n = 5–6. Statistical test: One-way ANOVA.