Fig 3. Candidate ladderane synthesis genes from Kuenenia stuttgartiensis and synthetic operon design.

(Top) Candidate genes identified by Rattray et al. [11] in native gene clusters with locus tags (adapted from [11]). (Bottom) Synthetic operons designed in this study containing candidate genes grouped by putative function or native gene clusters. Locus tags (without the kuste prefix) are shown for most genes in the synthetic operons; more details are given in Table 2.