Figure 1.

Injection of 11.5 mM NaHCO₃ into Oocytes Causes Enhancement of SLAC1-Mediated Anion Channel Currents When SLAC1 Is Coexpressed with OST1, While SLAC1 Expression Alone or Water-Injected Oocytes Did Not Show Significant HCO₃⁻ Regulation.

(A) Whole-cell currents were recorded from oocytes expressing the indicated cRNAs. During recordings of SLAC1 anion currents, single voltage pulses were applied in −20-mV decrements from +40 to −160 mV for 4 s, and the holding potential was 0 mV.

(B) Steady state current-voltage relationships from oocytes recorded as in (A). Numbers of oocytes recorded for each condition in the same batch of oocytes are provided in the current-voltage panels in all figures. Data are mean ± se. For some data points, the symbols are larger than the se in (B). Results from over six independent batches of oocytes showed similar results.