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. 2004 Aug;78(16):8868–8877. doi: 10.1128/JVI.78.16.8868-8877.2004

FIG. 6.

FIG. 6.

GALV RBD transactivates PERV-A and PERV-B infections of cells that lack functional PERV receptors. (A) Rat XC and MDTF/FePit1 cells are completely resistant to PERV-A (open bars, see arrows) but become susceptible in the presence of GALV RBD (black stipled bars) or Friend MuLV RBD (striped bars). (B) FEA and HeLa cells are completely resistant to PERV-B but become susceptible in the presence of a transactivating GALV RBD. The data are the averages of four experiments ± standard errors of the means. Ga, GALV; GadelH, ΔH GALV; Fe, FeLV-B; MO, Mo-MuLV; ModelH, ΔH Mo-MuLV. The arrows represent assays that indicated there was no infection.