Fig 1. Reduced glucose availability limits inflammatory responses to pathogen-associated molecular patterns.
(a-d) Ex vivo organ cultures of endometrium were cultured for 24 h in media containing 0 to 1.8 mg/organ glucose, with control vehicle or challenged with media containing 100 ng/ml LPS, PAM or FSL-1. At the end of the experiment organ weights were recorded and the accumulation of IL-1β (a), IL-6 (b), IL-8 (c) and LDH (d) measured in supernatants. Data are presented as mean + SEM concentration per mg tissue from 4 independent experiments, and analyzed by ANOVA, with P values reported above each treatment.