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. 2004 Aug;78(16):8753–8760. doi: 10.1128/JVI.78.16.8753-8760.2004

FIG. 2.

FIG. 2.

Depletion of Vβ14+ T cells reduces pulmonary eosinophilia in vvGs-immunized mice but not in FI-RSV-immunized mice. Mice were immunized with vvGs or FI-RSV and challenged with live RSV 6 weeks later. At days −1, 2, and 5 around RSV challenge, anti-Vβ14 antibody or IgM isotype control was administered. Seven days after challenge, BAL was performed, cells were stained, and differential cell counts were performed. The data represent the means ± standard deviations of the percentage of eosinophils (A) and the total number of eosinophils present in the BAL compartment (B). n = 5 mice per group from one of two experiments. Statistical analyses resulted in the following P values when IgM- and anti-Vβ14-treated mice from each priming group were compared. For vvGs-primed mice, P = 0.008 and 0.04 (percentage of eosinophils and total number of eosinophils, respectively). For FI-RSV-immunized mice, P = 0.176 and 0.91 (percentage of eosinophils and total number of eosinophils, respectively).