Fig. 1.

Workflow of the parcellation analysis. (A) A seed region objectively capturing RTPJ’s functional diversity was obtained by combining clusters of converging brain activity from three independent quantitative meta-analyses (Bzdok et al., 2012b; Jakobs et al., 2012; Langner and Eickhoff, in press). (B) The cross-correlation matrix (1736 × 1736 voxels) illustrates the similarity between the whole-brain connectivity profiles of any two seed voxels, computed separately based on voxel-wise MACM and RSFC analysis. Spectral reordering yielded sets of seed voxels that were strongly correlated with each other and weakly correlated with the rest of the matrix. (C) Quantitative CBP was performed on the combined seed region by hierarchical cluster analysis, yielding two distinct clusters of homogeneous connectivity. Importantly, those clusters were highly congruent between MACM and RSFC. All subsequent analyses were conducted on the intersection between anterior respectively posterior clusters derived from MACM- and RSFC-CBP.