Figure 4.
Reactivation kinetics of soman-inhibited human AChE mutant Y337A/F338A by bispyridinium aldoximes (HI-6, ICD-585 and K237) and pyridinium-imidazole aldoximes (RS-170B and RS-95C). Structures are shown in Figure 3. A mean of at least three experiments is presented. Reactivation constants were determined by nonlinear regression of experimental data and are presented in Table 4.