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. 2016 Jan;10(1):96–120.

Figure 2. Identified candidate genes in atopic dermatitis.

Figure 2

FLG, Filaggrin; SPINK5, Serine Protease Inhibitor Kazal-Type 5 ; MHC, major histocompatibility complex; HLA, human leukocyte antigen; CARD4, Caspase recruitment domain-containing protein 4; NOD, nucleotide binding oligomerization domain protein; CD, cluster of differentiation; MBL2, mannose binding lectin-2; TLR, toll like receptor; DEFB1, human defernsin 1; IL, interleukin; IL-4Rα, interleukin 4 receptor alpha; STAT6, signal transducer and activator of transcription-6; TNF, tumor necrosis factor; IFNγ, interferon gamma; IL1RN, interleukin 1 receptor antagonist; ST2, suppression of tumorigenicity-2; TGF, transforming growth factor; GM-CSF, granulocyte macrophage colony stimulating factor; CCL, chemokine C-motif ligand; CCR, chemokine C motif receptor; CMA1; mast cell chymase 1; GSTP1, clutathionine S-transferase P1; NAT, N-acetyl transferase; CTLA4, cytotoxic T-lymphocyte associated antigen-4; KLK, kallikrein; RUNX1, runt-related transcription factor 1; TRF-2, interferon regulatory factor 2; FCER1B, high affinity IgE receptor beta chain; PHF11, plant homeodomain zink finger 11 protein 11.