Skip to main content
. 2015 Nov 30;6(41):43202–43215. doi: 10.18632/oncotarget.6439

Figure 6. PGC-1α overexpression prevents cachexia in LLC-bearing mice.

Figure 6

Gastrocnemius (GSN), tibialis (TIB) and heart weight A. and tibialis fiber CSA B. in female control WT (C WT), PGC (C PGC) and LLC-bearing mice WT (LLC WT) and PGC (LLC PGC). Data (mean±SD) are expressed as percentages of C WT. C. Gene expression analysis of Atrogin-1 and MuRF1 transcripts. Specific mRNA abundance was corrected for the mean of TBP (TATA box-binding protein) and β-actin levels on individual samples. Data (means ± SE) are compared by 2-way ANOVA. Significance of the differences: *p< 0,05 vs C WT, **p < 0,01 vs C WT, ***p < 0,001 vs C WT, $p < 0,05 vs LLC WT, #p < 0,05 vs C PGC, ##p < 0,01 vs C PGC.