Table 2. Comparison of mutation profiles using Ampliseq (MAF > 0.1).

Data set	Group 1 vs Group 2	Gene	Group 1 wild	Group 1 mut	Group 2 wild	Group 2 mut	P value	Group 1 ratio	Group 2 ratio
All (N = 60)	Brain vs Breast	TP53	17	25	11	7	0.167	0.5952	0.3889
		RB1	39	3	14	4	0.182	0.0714	0.2222
Pair (N = 15)	Brain vs Breast	RB1	14	1	11	4	0.330	0.0667	0.2667
		SMAD4	15	0	13	2	0.483	0	0.1333