Table 2. Comparison of mutation profiles using Ampliseq (MAF > 0.1).
Data set | Group 1 vs Group 2 | Gene | Group 1 wild | Group 1 mut | Group 2 wild | Group 2 mut | P value | Group 1 ratio | Group 2 ratio |
---|---|---|---|---|---|---|---|---|---|
All (N = 60) | Brain vs Breast | TP53 | 17 | 25 | 11 | 7 | 0.167 | 0.5952 | 0.3889 |
RB1 | 39 | 3 | 14 | 4 | 0.182 | 0.0714 | 0.2222 | ||
Pair (N = 15) | Brain vs Breast | RB1 | 14 | 1 | 11 | 4 | 0.330 | 0.0667 | 0.2667 |
SMAD4 | 15 | 0 | 13 | 2 | 0.483 | 0 | 0.1333 |