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. 2015 Oct 19;6(41):44019–44029. doi: 10.18632/oncotarget.5806

Table 1. Baseline characteristics of nasopharyngeal carcinoma patients treated with intensity-modulated radiotherapy with or without concurrent chemotherapy.

The original unmatched cohort The propensity-matched cohort
IMRT alone (N = 254) IMRT+CC (N = 407) P Standardized difference IMRT alone (N = 241) IMRT+CC (N = 241) P Standardized difference
No. % No. % No. % No. %
Age 0.021 0.181 0.894 0.012
Mean 48.31 46.24 47.99 47.85
SD 12.30 10.49 12.22 10.31
Median 46.50 45.00 46.00 47.00
Sex 0.540 0.049 0.917 0.009
Male 189 74.4 294 72.2 179 74.3 180 74.7
Female 65 25.6 113 27.8 62 25.7 61 25.3
Histology* 0.501 0.055 0.611 0.046
II 8 3.1 17 4.2 7 2.9 9 3.7
III 246 96.9 390 95.8 234 97.1 232 96.3
VCA-IgA 0.160 0.628
<80 69 27.2 89 21.9 0.123 61 25.3 59 24.5 0.019
80–320 94 37.0 145 35.6 0.029 90 37.3 82 34.0 0.069
≥320 91 35.8 173 42.5 0.137 90 37.3 100 41.5 0.085
EA-IgA 0.107 0.592
<10 111 43.7 147 36.1 0.155 102 42.3 97 40.2 0.042
10–40 80 31.5 134 32.9 0.031 78 32.4 73 30.3 0.045
≥40 63 24.8 126 31.0 0.138 61 25.3 71 29.5 0.093
T-stage < 0.001 0.701
T1 74 29.1 96 23.6 0.126 73 30.3 69 28.6 0.036
T2 140 55.1 186 45.7 0.189 128 53.1 125 51.9 0.025
T3 40 15.7 125 30.7 0.360 40 16.6 47 19.5 0.076
N-stage 0.503 0.053 0.296 0.095
N0 104 40.9 156 38.3 92 38.2 81 33.6
N1 150 59.1 251 61.7 149 61.8 160 66.4
Clinical stage < 0.001 0.360 0.407 0.075
II 214 84.3 282 69.3 201 83.4 194 80.5
III 40 15.7 125 30.7 40 16.6 47 19.5

Abbreviations: IMRT = intensity-modulated radiotherapy, CC = concurrent chemotherapy, SD = standard deviation, VCA = viral capsid antigen, EA = early antigen, IgA = immunoglobulin A

*

Based on the criteria of WHO histological type (1991): II - Differentiated non-keratinising carcinoma, III - Undifferentiated non-keratinising carcinoma

In accordance with the criteria adopted in previous studies