Acellular dermal matrix |
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Allograft |
AlloDerm® (LifeCell Corp, Branchburg, New Jersey, USA); AlloDerm® Ready to Use (LifeCell Corp., Branchburg, New Jersey, USA) |
Cadaveric |
Non-sterile, aseptic; |
• Freeze dried or pre-hydrated; |
• Potential allergen—multiple antibiotics are used in product processing |
• Most documented in literature |
• Orientation specific; |
• Infero-lateral sling; |
Terminally sterilized |
• Immediate implant or expander based reconstruction; |
• Nipple reconstruction; |
• Shelf life 2 years |
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FlexHD® (MTF/Ethicon, Somerville, New Jersey, USA) |
Cadaveric |
Non-sterile, aseptic |
• Pre-hydrated; |
• No information available (NIA) |
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• Orientation specific; |
• Mainly used for abdominal reconstruction; |
• Shelf life 3 years |
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DermaMatrix® (MTF/Synthes, West Chester, Pennsylvania, USA) |
Cadaveric |
Non-sterile, aseptic |
• Freeze dried; |
• Not recommended in patients with autoimmune connective tissue disease |
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• Orientation specific; |
• Immediate implant or expander based reconstruction; |
• Shelf life 3 years |
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AlloMax™ (Bard, Warwick, Rhode Island, USA) |
Cadaveric |
Terminally sterilized |
• Freeze dried; |
• NIA |
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• Not orientation specific; |
• Immediate implant or expander based reconstruction; |
• Shelf life 5 years |
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DermaCell® (Lifenet, Virginia Beach, Virginia, USA) |
Cadaveric |
Non-sterile, aseptic |
• Ready to use; |
• Sensitivities to gentamicin and vancomycin |
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• Orientation specific; |
• Nipple reconstruction; |
• Shelf life 2 years |
Xenograft |
PermaCollTM (Covidien, Boulder, Colorado, USA) |
Porcine |
Terminally sterilized |
• Pre-hydrated; |
• Sensitivities to porcine tissue |
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• Not orientation specific; |
• Mainly used for abdominal reconstruction; |
• Not recommended for breast reconstruction due to inadequate laxity |
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StratticeTM (Lifecell, Branchburg, New Jersey, USA) |
Porcine |
Terminally sterilized |
• Pre-hydrated; |
• Sensitivities to porcine tissue |
• Highest stiffness and tensile strength of all the acellular dermal matrices (ADMs) |
• Not orientation specific; |
• Mainly used for abdominal reconstruction; |
• Shelf life 18 months |
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SurgiMend® PRS (TEI Biosciences, Boston, Massachusetts, USA) |
Fetal Bovine |
Terminally sterilized |
• Pre-hydrated; |
• Sensitivities to bovine tissue |
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• Not orientation specific; |
• Shelf life 3 years |
Synthetic mesh |
TiLOOP® Bra (PFM Medical, Cologne, Germany) |
Titanium coated polypropylene mesh |
Terminally sterilized |
• Infra-mammary fold like shape; |
• Not suitable for revision surgery |
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• Comes in three sizes; |
• Mainly available in Europe—not yet approved in the United States as of July 2013 |
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TIGR Matrix Surgical Mesh (Novus Scientific Pte Ltd, Singapore) |
Fast-degrading (copolymer of glycolide and trimethylene carbonate) and slow-degrading (copolymer of lactide and trimethylene carbonate) fibers |
Terminally sterilized |
• Long term, absorbable, macroporous knitted mesh; |
• Higher complication rates in irradiated patients |
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• Retains mechanics for up to 9 months; |
• Totally hydrolysed by 3 years |
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Knitted Vicryl Mesh (Vicryl, Ethicon, Somerville, New Jersey, USA) |
Polyglactin 910 |
Terminally sterilized |
• Absorbable; |
• Higher complication rates in irradiated patients |
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• Ready to use; |
• Cheap and widely available; |
• Minimum inflammatory response and non-allergenic |