Table 4.

Electroretinography latencies and amplitudes in Wilson disease with and without pathological changes in brain MRI

	WD Group						CG and MRI-
	MRI+ (N = 39)		MRI− (N = 19)		MRI+ vs. MRI-		CG		MRI- vs. CG
Parameter	Mean	SD	Mean	SD	Difference	p	Mean	SD	Difference	p
Dark-adapted 0.01
sc b lat. (ms)	87.96	5.50	81.41	3.29	6.55	<0.001	78.42	5.49	2.99	0.023
sc b amp. (μV)	204.53	56.62	242.00	59.21	−37.47	0.033	242.83	56.73	−0.83	0.926
Dark-adapted 3.0
sc max a lat. (ms)	21.82	1.62	19.77	1.70	2.05	<0.001	20.99	1.24	−1.22	0.004
sc max a amp. (μV)	238.38	74.64	271.32	81.98	−32.94	0.117	343.37	35.50	−72.05	0.001
sc max b lat. (ms)	45.09	2.99	41.72	2.67	3.37	<0.001	40.54	3.43	1.18	0.377
sc max b amp. (μV)	444.85	118.10	492.50	133.60	−43.65	0.232	562.60	76.99	−70.1	0.058
O1 lat. (ms)	20.03	2.23	18.39	0.87	1.64	0.001	18.21	0.46	0.18	0.418
O1 amp. (μV)	22.19	7.65	28.69	8.43	− 6.5	0.008	30.66	5.31	−1.97	0.371
O2 lat. (ms)	25.76	1.43	24.56	0.90	1.2	0.001	24.73	0.93	−0.17	0.542
O2 amp. (μV)	52.27	23.40	68.13	29.84	- 15.86	0.049	95.50	24.16	−27.37	0.006
O3 lat. (ms)	32.50	1.33	31.73	1.03	0.77	0.030	31.49	0.90	0.24	0.417
O3 amp. (μV)	23.02	11.65	27.88	14.30	−4.86	0.377	49.92	17.68	−22.04	<0.001
Light-adapted 3.0
pht a lat. (ms)	16.23	1.12	15.46	0.70	0.77	0.001	15.03	0.60	0.43	0.018
pht a amp. (μV)	43.48	14.34	56.75	14.07	−13.27	0.002	56.08	8.46	0.67	0.853
pht b lat. (ms)	31.34	0.96	30.46	1.16	0.85	0.008	30.45	1.06	0.01	0.983
pht b amp. (μV)	167.66	40.45	203.95	53.80	−36.29	0.015	234.47	41.01	−30.52	0.043

MRI magnetic resonance image; MRI+ patients with pathological findings on MRI, MRI- patients without pathological findings on MRI, CG control group, sc b lat. b wave latency, sc b amp b-wave amplitude. Lat. latency, amp. amplitude, O1, O2, O3 first, second and third oscillatory potential respectively, SD standard deviation, ms milliseconds, μV microvolts. Statistically significant differences are represented in bold